Dr. Duplantier is a medicinal chemist with 20 years of industry and 8 years of government experience in drug discovery and development. He has worked in all stages of early drug development including hit-to-lead, lead optimization, candidate selection and IND submission. He was a Laboratory Supervisor and Design Lead at Pfizer in the therapeutic areas of neuroscience, inflammation, allergy, and respiratory diseases, and had leadership roles on a variety of multi-disciplinary project teams. These efforts led to the delivery of four clinical drug candidates giving him the opportunity to be part of several clinical candidate development teams. Dr. Duplantier spent 2 years as a Senior Advisor at DTRA where he managed the discovery and development of medical countermeasures (MCMs) to chemical weapons, was personally responsible for a $32M per year portfolio of projects, and lead a team to stand up an ADME center for the DoD. More recently, as a contractor at USAMRIID he has had leadership roles in the identification and optimization of therapeutics for the treatment of viral and bacterial infections, and toxin poisoning. He was a key contributor to USAMRIID’s recent COVID-19 outbreak and 2014 EBOV outbreak responses to rapidly assess, evaluate, and prioritize externally partnered therapeutics. He is an Adjunct Lecturer for Johns Hopkins University’s Advanced Academic Programs. He has published over 60 research articles, book chapters, and patent applications.
Dr. Duplantier received a Ph.D. in Organic Chemistry from the Massachusetts Institute of Technology, and a B.S. in Chemistry from the University of New Orleans.